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1. Hopelessness; a hopeless state; a destitution of hope or expectation.

We are perplexed, but not in despair 2 Corinthians 4:8.

All safety in despair of safety placed.

2. That which causes despair; that of which there is no hope.

The mere despair of surgery, he cures.

3. Loss of hope in the mercy of God.

DESPAIR, verb intransitive [Latin To hope.] To be without hope; to give up all hope or expectation; followed by of.

We despaired even of life. 2 Corinthians 1:8.

Never despair of Gods blessings here, or of his reward hereafter.