American Dictionary of the English Language

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SLOUGH, noun slou.

1. A place of deep mud or mire; a hole full of mire.

2. [pron. sluff.] The skin or cast skin of a serpent. [Its use for the skin in general, in Shakespeare, is not authorized.]

3. [pron. sluff.] The part that separates from a foul sore. The dead part which separates from the living in mortification.

SLOUGH, verb intransitive sluff. To separate from the sound flesh; to come off; as the matter over a sore; a term in surgery.

TO slough OFF, to separate from the living parts, as the dead part in mortification.