1. Extreme malice; violent hatred; malignity; malice irritated or enraged; active malignity; angry hatred.
With all thy despite against the land of Israel. Ezekiel 25:6.
2. Defiance with contempt, or contempt of opposition.
He will rise to fame in despite of his enemies.
3. An act of malice or contempt; as a despite to the Most High.
DESPITE, verb transitive To vex; to offend; to tease.