Shrew
SHREW, noun
1. A peevish, brawling, turbulent, vexatious woman. It appears to have originally been applied to males as well as females; but is now restricted to the latter.
The man had got a shrew for his wife, and there could be no quiet in the house with her. L'Estrange.
2. A shrew-mouse.
SHREW, verb transitive To beshrew; to curse. Obs.